Highlights

  • Reproducibility in Brazil

    The results of a project to estimate the reproducibility of research in Brazil have just been published.

    Interview
  • Exploring vascular disease

    Interactions between fibroblast cells and smooth muscle cells have a central role in the development of pulmonary hypertension.

    Slaven Crnkovic, Helene Thekkekara Puthenparampil ... Grazyna Kwapiszewska
    Research Article
  • Looking at lens development

    A study in mice reveals key interactions between the proteins involved in fibroblast growth factor (FGF) signaling and how they contribute to distinct stages of eye lens development.

    Qian Wang, Hongge Li ... Xin Zhang
    Research Article

Latest research

    1. Developmental Biology

    Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

    Madeline M Keenen, Liheng Yang ... Carolyn B Coyne
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Evidence for systematic - yet task- and motor-contingent - rhythmicity of auditory perceptual judgements

    Cécile Fabio, Christoph Kayser
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Magnetically steered cell therapy for reduction of intraocular pressure as a treatment strategy for open-angle glaucoma

    M Reza Bahrani Fard, Jessica Chan ... C Ross Ethier
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation

    Human giant GTPase GVIN1 forms an antimicrobial coatomer around the intracellular bacterial pathogen Burkholderia thailandensis

    Weilun Guo, Shruti S Apte ... Jörn Coers
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Biochemistry and Chemical Biology

    Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response

    CJ San Felipe, Jyoti Batra ... James S Fraser
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Evolutionary Biology

    Unprecedented Number of Recurrent Mutations Drive the Rapid Evolution of Pesticide Resistance in a Notorious Pest

    Li-Jun Cao, Jin-Cui Chen ... Shu-Jun Wei
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Sparse innervation and local heterogeneity in the vibrissal corticostriatal projection

    Kenza Amroune, Lorenzo Fontolan ... Ingrid Bureau
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Heritability of movie-evoked brain activity and connectivity

    David C Gruskin, Daniel J Vieira ... Gaurav H Patel
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

    Yevheniia Ishchenko, Amanda T Jeng ... Anthony J Koleske
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Structural Biology and Molecular Biophysics

    Protein Language Model Identifies Disordered, Conserved Motifs Driving Phase Separation

    Yumeng Zhang, Jared Zheng, Bin Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling